Legend®
Legend® (hyaluronate sodium) is the joint disease therapy that helps reduce acute inflammation and reduces the likelihood of chronic joint damage. Legend is pure hyaluronate sodium, the same glycosaminoglycan present in normal joint fluid to protect and lubricate joint cartilage and soft tissues. Legend is produced by a patented biofermentation process, resulting in such purity that it can be given intravenously for immediate bioavailability.
Key Benefits
Legend, because of its unique purity, can be given intra-articularly or intravenously. I.V. administration provides the following advantages:
- Safety
- No need to invade the joint with a needle, risking bacterial entrance, physical trauma to joint tissues or intra-articular injection reactions.
- Safety in breeding animals has not been determined.
- Federal law restricts this drug to use by or on the order of a licensed veterinarian.
- For use only in horses. Do not use in horses intended for human consumption.
- Convenience
- No shaving or surgical preparation of the joint.
- IV administration to treat multiple joints.
- Available in a larger, 20mL Multi Dose vial for Intravenous use only.
- Efficacy
- Proven to decrease inflammation and destructive enzymes associated with inflammation.1
- Rapid onset of action. I.V. administration helps ensure a quick onset of action resulting in a rapid decrease in inflammation.
- Applications
- Legend 2mL, For Intravenous and Intra-Articular use
- Legend 4mL, For Intravenous use only
- Legend Multi 20mL, For Intravenous use only
The intra-articular safety of Legend Multi dose with benzyl alcohol has not been determined.
Footnotes
- Kawcak, C.E., Frisbie, D.D., Trotter, G.W., McIlwraith, C.W., Gillette, S.M., Powers, B.E., Walton, R.M.: Effects of intravenous administration of hyaluronate sodium on carpal joins in exercising horses after arthroscopic surgery and osteochondral fragmentation. AJVR. Vol, 58, No. 10, October 1997.