Member Login

E-mail / Login ID:

Password:





Not a member?

Forgot your password?

Are you a pet owner?

Find Information By:

Other Bayer Sites

Conditions of Use

Privacy Statement

Imprint

Don't let BRD kill chances for a strong finish.

Producers tell us their biggest concerns are death loss and chronics.1

Producers tell us their biggest concerns are death loss and chronics.

  • Baytril 100 is the first FDA-approved fluoroquinolone for the treatment of bovine respiratory disease (BRD) and outsells every antibiotic in its class.2
  • Baytril 100 is bactericidal, killing the major BRD-causing bacteria, including: Mannheimia haemolytica, Pasteurella multocida and Histophilus somni.
  • Baytril 100 In vitro,* Baytril 100 kills 97 percent of BRD-causing bacteria in 1-2 hours.3,4
  • In cattle, Baytril 100 reaches therapeutic levels at the site of infection in the lungs in 1-2 hours.5
  • Baytril 100 has a unique mode of action. Enrofloxacin, its active ingedient, penetrates the bacteria cell and binds the DNA gyrase, resulting in cell death.
  • Baytril 100 kills bacteria in both its resting and growth phases of bacterial development.6
  • Baytril 100 is concentration-dependent. In vitro* studies demonstrate that the higher the Baytril 100 concentration, the faster it kills. 3,4,7
  • Baytril 100 injects easily, especially in cold weather (protect from freezing), and is easy on the calf, with no significant injection site reactions.8
  • Baytril 100 works as a single-injection or as a multiple-day therapy.

Do not use in calves to be processed for veal. Extra-label use in food-producing animals is prohibited. Cattle intended for human consumption must not be slaughtered within 28 days from the last treatment.

+Do not use in female dairy cattle 20 months of age or older. Use of Baytril 100 in this class of cattle may cause milk residues.

*The clinical significance of in vitro data has not been determined.


REFERENCES:

  1. 2008 Ipsos Forward Research, Baytril 100 Awareness, Attitudes, Use in Stockers.
  2. Data on file.
  3. Blondeau J.M., Borsos S., Blondeau L.D., Blondeau B.J., Hesje C. The killing of clinical isolates of Mannheimia haemolytica (MH) by enrofloxacin (ENR) using minimum inhibitory and mutant prevention drug concentrations and over a range of bacterial inocula. In: ASM Conference on Pasteurellaceae; 2005 October 23-26; Kohala Coast, Big Island, Hawaii: American Society of Microbiology; 2005. Abstract B12.
  4. Blondeau J.M., Borsos S.D., Hesje C.H., Blondeau L.D., Blondeau B.J. Comparative Killing of Bovine Isolates of Mannheimia haemolytica by Enrofloxacin, Florfenicol Tilmicosin and Tulathromycin Using the Measured Minimum Inhibitory Concentration (MIC) and Mutant Prevention Concentration (MPC) Drug Values. In: International Meeting of Emerging Diseases and Surveillance (IMED), Vienna, Austria, February 23-25, 2007. Figures 8-10.
  5. Davis J.L., Foster D.M., Papich M.G. Pharmacokinetics and tissue distribution of enrofloxacin and its active metabolite ciprofloxacin in calves. J. vet. Pharmacol. Therap. 30, 564-571.
  6. Claus G.W. (1995). In: G. R. Carter, M. M. Chengappa, and A. W. Roberts (Eds.). Microbial Nutrition, Metabolism, and Growth. Essentials of Veterinary Microbiology. Williams & Wilkins, Philadelphia. p. 39.
  7. Concentration-dependent Killing Activity of Baytril® 100 (enrofloxacin). Bayer Study, BL04195 (Pirro et al., BCVA Autumn Meeting, Glasgow, October 2000).
  8. Syringability and Viscosity Testing of Baytril 100 Injectable Solution - Report 03-02 (BL3168).

Additional Baytril 100 Cattle Information