Advantage® II for cats

Not a veterinary professional?

Get the information you need about this product on our site designed especially for pet owners.


Advantage® II is a topical flea control for cats that kills fleas through contact, so fleas do not have to bite to die. Advantage® II kills fleas rapidly within 12 hours of initial application. Reinfesting fleas are killed within 2 hours with protection against further flea infestation lasting for up to a month. Pyriproxyfen provides the additional benefit of killing flea eggs and larvae to effectively break the flea life cycle. For use on cats and kittens 8 weeks of age and older, weighing 2 lbs. or more.

Key benefits

  • Kills multiple flea life stages
  • Treats existing and prevents further infestations
  • Kills fleas within 12 hours of initial application
  • Kills reinfesting fleas within 2 hours
  • Works through contact, so fleas don’t have to bite to die
  • Waterproof
  • Easy to apply topical application
  • ParasitologyParasitology


  • Flea eggs
  • Flea infestations
  • Flea larvae
  • Fleas

Advantage® II for cats FAQs

What is an insect growth regulator?

How does pyriproxyfen work in Advantage® II for cats?

Why is it important to use a product like Advantage® II for cats with an IGR?

What are the Advantage® II for cats product weight bands?

What are the packaging specifications for Advantage® II for cats?

Advantage Multi® for Cats (imidacloprid + moxidectin)
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Cats (imidacloprid + moxidectin) to use by or on the order of a licensed veterinarian. WARNINGS: Do not use on sick or debilitated cats. Do not use on underweight cats. (see ADVERSE REACTIONS). Do not use on cats less than 9 weeks of age or less than 2 lbs body weight. PRECAUTIONS: Avoid oral ingestion. HUMAN WARNINGS: Children should not come in contact with the application site for 30 minutes after application.

Profender® (emodepside/praziquantel) Topical Solution
CAUTION: Federal law (U.S.A.) restricts this drug to use by or on the order of a licensed veterinarian. HUMAN WARNINGS: Children should not contact application site for twenty-four (24) hours.

Veraflox® (pradofloxacin) Oral Suspension for Cats
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Federal law prohibits the extra label use of this drug in food-producing animals. CONTRAINDICATIONS: Do not use in dogs. Pradofloxacin has been shown to cause bone marrow suppression in dogs. Pradofloxacin is contraindicated in cats with a known hypersensitivity to quinolones. WARNINGS: Not for human use. Keep out of reach of children. For use in cats only. The administration of pradofloxacin for longer than 7 days induced reversible leukocyte, neutrophil, and lymphocyte decreases in healthy, 12-week-old kittens. PRECAUTIONS: The use of fluoroquinolones in cats has been associated with retinopathy or blindness. Such products should be used with caution in cats. Refer to the product label for a more complete list of risks and precautions.

Advantage is a registered trademark of Bayer.