Advantage Multi® (imidacloprid + moxidectin) for Dogs & Cats

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Prescribing Information for Veterinary Professionals
Advantage Multi® (imidacloprid + moxidectin) provides broad-spectrum parasite protection in a convenient monthly topical application, potentially increasing compliance for dogs and cats that may not prefer oral medications.

For dogs, Advantage Multi® prevents heartworm disease and treats heartworm microfilaria, kills fleas and treats and controls roundworms, hookworms, whipworms and sarcoptic mange. For cats, Advantage Multi® kills fleas, treats and controls ear mites, roundworms and hookworms and prevents heartworm disease — all in one easy-to-use topical application. Plus, it’s the only FDA-approved product indicated for ferrets for the treatment of fleas and prevention of heartworm disease.

  • ParasitologyParasitology


  • Ear mites
  • Fleas
  • Heartworm microfilaria
  • Heartworms
  • Hookworms
  • Roundworms
  • Sarcoptic mange
  • Whipworms

CAUTION: Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.

Dogs: WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application, ensure that dogs cannot lick the product from application sites on themselves or other treated animals. (See Contraindications and Adverse Reactions for more information.)

Cats and ferrets: WARNING: Do not use on sick or debilitated cats or ferrets. Do not use on underweight cats. (See Contraindications and Adverse Reactions for more information.) Do not use on cats less than 9 weeks of age and cats or ferrets less than 2 lbs. body weight.

PRECAUTIONS: Avoid oral ingestion.

HUMAN WARNINGS: Children should not come in contact with application sites for 2 hours after application.

Advantage Multi® for Dogs & Cats FAQs

Does Advantage Multi® protect against heartworms even after your patient gets wet?

Some of my patients weigh more than the largest available size of Advantage Multi® for Dogs or Advantage Multi® for Cats. Can I still recommend Advantage Multi®?

Is Advantage Multi® for Cats a suitable parasite protection for ferrets?

What are the packaging specifications for Advantage Multi®?

What are the dosing and frequency guidelines for Advantage Multi®?

What are the active ingredients in Advantage Multi®?

Why should I prescribe Advantage Multi®?

Advantage Multi is a registered trademark of Bayer.